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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

A comparative trial of liquid lomotil and mist kaolin in childhood diarrhoea.

Lomotil liquid in a dose of 0.3 mg/kg/day has been compared with plain mist kaolin in controlling acute diarrhoea in young children aged 6 weeks to 2 years. Lomotil was found to stop the diarrhoea faster and significantly shorten the period of hospital admission than kaolin (P less than 0.05) in children whose diarrhoea was complicated by moderate dehydration. In those with mild dehydration lomotil had no advantage over kaolin. Children with severe dehydration treated with lomotil spent on the average much shorter period in hospital than those on kaolin, but the numbers were too small to allow for useful comparison. There was no adverse effect observed in any of subjects at the dose of lomotil used.[1]

References

  1. A comparative trial of liquid lomotil and mist kaolin in childhood diarrhoea. Johnson, A.O., Effiong, C.E., Bamidele, M.A. African journal of medicine and medical sciences. (1977) [Pubmed]
 
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