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Milligan, D.W. et al.

Lung function in children following repair of tracheoesophageal fistula.

Lung function and bronchial reactivity by methacholine challenge were studied in 24 patients seven to 18 years after repair of type I tracheoesophageal fistula. Only one patient had no abnormalities of the variables tested. Thirteen patients had obstructive airways disease, five had a restrictive defect, and 15 had a positive methacholine challenge. It is postulated that continuing subclinical aspiration of esophageal contents causes lung damage and renders the airways hyperreactive.[1]

References

Lung function in children following repair of tracheoesophageal fistula. Milligan, D.W., Levison, H. J. Pediatr. (1979) [Pubmed]

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