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Melvin, W.T. et al.

Affinity chromatography of thiol-containing purines and ribonucleic acid.

Evidence is presented for the specific interaction of 6-mercaptopurine with mercurated cellulose. Following from this, a new method is described for the affinity chromatography of thiol-containing molecules and of RNA containing incorporated 6-thioguanosine on columns of mercurated cellulose. This technique may find application in the study of RNA metabolism and gene expression.[1]

References

Affinity chromatography of thiol-containing purines and ribonucleic acid. Melvin, W.T., Keir, H.M. Biochem. J. (1977) [Pubmed]

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