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Staddon, J.M. et al.

Effects of glucagon in vivo on the N-acetylglutamate, glutamate and glutamine contents of rat liver.

Glucagon injected into rats caused an increase in liver N-acetylglutamate content, and coincidentally the glutamate content decreased. The liver glutamine content decreased only after 10 min, consistent with an activation of glutaminase after a lag. These observations indicate that the increased N-acetylglutamate content was not due to an increase in glutamate content caused by an activation of glutaminase (EC 3.5.1.2).[1]

References

Effects of glucagon in vivo on the N-acetylglutamate, glutamate and glutamine contents of rat liver. Staddon, J.M., Bradford, N.M., McGivan, J.D. Biochem. J. (1984) [Pubmed]

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