Chemical Compound Review:
glutamin 2-amino-4-aminocarbonyl- butanoic acid
Synonyms:
Hgln, L-Glutamid, DL-Glutamine, H-DL-Gln-OH, DL Glutamine, ...
- Glutamine-stimulated modification and degradation of glutamine synthetase in hepatoma tissue culture cells. Arad, G., Freikopf, A., Kulka, R.G. Cell (1976)
- The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Tsuda, H., Jafar-Nejad, H., Patel, A.J., Sun, Y., Chen, H.K., Rose, M.F., Venken, K.J., Botas, J., Orr, H.T., Bellen, H.J., Zoghbi, H.Y. Cell (2005)
- Bacillus subtilis glutamine synthetase controls gene expression through a protein-protein interaction with transcription factor TnrA. Wray, L.V., Zalieckas, J.M., Fisher, S.H. Cell (2001)
- No effect of L-glutamine on cystinuria. Skovby, F., Rosenberg, L.E., Thier, S.O. N. Engl. J. Med. (1980)
- Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. Imbert, G., Saudou, F., Yvert, G., Devys, D., Trottier, Y., Garnier, J.M., Weber, C., Mandel, J.L., Cancel, G., Abbas, N., Dürr, A., Didierjean, O., Stevanin, G., Agid, Y., Brice, A. Nat. Genet. (1996)
- Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion. White, J.K., Auerbach, W., Duyao, M.P., Vonsattel, J.P., Gusella, J.F., Joyner, A.L., MacDonald, M.E. Nat. Genet. (1997)
- Oral glutamine challenge in cirrhotics pre- and post-liver transplantation: a psychometric and analyzed EEG study. Oppong, K.N., Al-Mardini, H., Thick, M., Record, C.O. Hepatology (1997)
- Noncirrhotic portal vein thrombosis exhibits neuropsychological and MR changes consistent with minimal hepatic encephalopathy. Mínguez, B., García-Pagán, J.C., Bosch, J., Turnes, J., Alonso, J., Rovira, A., Córdoba, J. Hepatology (2006)
- Pentagastrin induced motility pattern in the human upper gastrointestinal tract is reversed by proglumide. Erckenbrecht, J.F., Caspari, J., Wienbeck, M. Gut (1984)
- Molecular basis of celiac disease. Sollid, L.M. Annu. Rev. Immunol. (2000)
- Hyperalimentation in cancer. Souba, W.W., Copeland, E.M. CA: a cancer journal for clinicians. (1989)
- CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. Doye, A., Mettouchi, A., Bossis, G., Clément, R., Buisson-Touati, C., Flatau, G., Gagnoux, L., Piechaczyk, M., Boquet, P., Lemichez, E. Cell (2002)
- Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Osherovich, L.Z., Weissman, J.S. Cell (2001)
- Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4. Bentley, A.K., Rees, D.J., Rizza, C., Brownlee, G.G. Cell (1986)
- Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation. Megee, P.C., Morgan, B.A., Mittman, B.A., Smith, M.M. Science (1990)
- Astrocytic control of glutamatergic activity: astrocytes as stars of the show. Hertz, L., Zielke, H.R. Trends Neurosci. (2004)
- A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties. Nakanishi, N., Shneider, N.A., Axel, R. Neuron (1990)
- Glucose-derived osmolytes and energy impairment in brain edema accompanying liver failure: the role of glutamine reevaluated. Albrecht, J. Gastroenterology (2003)
- Sry requires a CAG repeat domain for male sex determination in Mus musculus. Bowles, J., Cooper, L., Berkman, J., Koopman, P. Nat. Genet. (1999)
- A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation. Geisterfer-Lowrance, A.A., Kass, S., Tanigawa, G., Vosberg, H.P., McKenna, W., Seidman, C.E., Seidman, J.G. Cell (1990)
- Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Zhuchenko, O., Bailey, J., Bonnen, P., Ashizawa, T., Stockton, D.W., Amos, C., Dobyns, W.B., Subramony, S.H., Zoghbi, H.Y., Lee, C.C. Nat. Genet. (1997)
- Novel subunit-subunit interactions in the structure of glutamine synthetase. Almassy, R.J., Janson, C.A., Hamlin, R., Xuong, N.H., Eisenberg, D. Nature (1986)
- Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial? Sisodia, S.S. Cell (1998)
- Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Imoto, K., Busch, C., Sakmann, B., Mishina, M., Konno, T., Nakai, J., Bujo, H., Mori, Y., Fukuda, K., Numa, S. Nature (1988)
- Glycyl glutamine, an inhibitory neuropeptide derived from beta-endorphin. Parish, D.C., Smyth, D.G., Normanton, J.R., Wolstencroft, J.H. Nature (1983)
- Protein biosynthesis in organelles requires misaminoacylation of tRNA. Schön, A., Kannangara, C.G., Gough, S., Söll, D. Nature (1988)
- Fibroblast adhesion to fibrinogen and fibrin substrata: requirement for cold-insoluble globulin (plasma fibronectin). Grinnell, F., Feld, M., Minter, D. Cell (1980)
- Tertiary structure is a principal determinant to protein deamidation. Kossiakoff, A.A. Science (1988)
- Proglumide: selective antagonism of excitatory effects of cholecystokinin in central nervous system. Chiodo, L.A., Bunney, B.S. Science (1983)
- HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA. Hoekstra, M.F., Liskay, R.M., Ou, A.C., DeMaggio, A.J., Burbee, D.G., Heffron, F. Science (1991)
- Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators. Hoey, T., Weinzierl, R.O., Gill, G., Chen, J.L., Dynlacht, B.D., Tjian, R. Cell (1993)
- The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1. Matilla, A., Koshy, B.T., Cummings, C.J., Isobe, T., Orr, H.T., Zoghbi, H.Y. Nature (1997)
- Unique structure of murine interleukin-2 as deduced from cloned cDNAs. Kashima, N., Nishi-Takaoka, C., Fujita, T., Taki, S., Yamada, G., Hamuro, J., Taniguchi, T. Nature (1985)
- Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Brunner, H.G., Nelen, M., Breakefield, X.O., Ropers, H.H., van Oost, B.A. Science (1993)
- A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases. Zhang, K.Y., Card, G.L., Suzuki, Y., Artis, D.R., Fong, D., Gillette, S., Hsieh, D., Neiman, J., West, B.L., Zhang, C., Milburn, M.V., Kim, S.H., Schlessinger, J., Bollag, G. Mol. Cell (2004)
- Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis. Clarke, A.R., Wigley, D.B., Chia, W.N., Barstow, D., Atkinson, T., Holbrook, J.J. Nature (1986)
- Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide. Watkins, L.R., Kinscheck, I.B., Mayer, D.J. Science (1984)
- The Aspergillus nidulans fluG gene is required for production of an extracellular developmental signal and is related to prokaryotic glutamine synthetase I. Lee, B.N., Adams, T.H. Genes Dev. (1994)
- Effect of bath and luminal potassium concentration on ammonia production and secretion by mouse proximal tubules perfused in vitro. Nagami, G.T. J. Clin. Invest. (1990)
- Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations. Sokolov, S., Scheuer, T., Catterall, W.A. Neuron (2005)