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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Cholecystokinin receptors in the brain: characterization and distribution.

Specific cholecystokinin binding sites in particulate fractions of rat brain were measured with iodine 125-labeled Bolton-Hunter cholecystokinin, a cholecystokinin analog that has full biological activity. Binding was detected in brain regions known to contain immunoreactive cholecystokinin. Binding was saturable, reversible, of high affinity (dissociation constant, 1.7 x 10(-9) M), and was inhibited by cholecystokinin analogs but not by unrelated hormones.[1]


  1. Cholecystokinin receptors in the brain: characterization and distribution. Saito, A., Sankaran, H., Goldfine, I.D., Williams, J.A. Science (1980) [Pubmed]
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