- Decreased activity of uroporphyrinogen decarboxylase caused by 2,4,5,3',4'-pentabromobiphenyl in chick embryo hepatocyte cultures. Difference in activity in intact or homogenized cells. Sinclair, P.R., Elder, G.H., Bement, W.J., Smith, S.G., Bonkowsky, H.L., Sinclair, J.F. FEBS Lett. (1983)