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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Formation of N-nitrosodiphenylamine from 1,1-diphenylhydrazine by rat liver microsomal preparations.

The present study provides the first evidence for in vitro metabolic conversion of a 1,1-disubstituted hydrazine to the corresponding nitrosamine. The study shows that superoxide radical which is generated by NADPH-cytochrome c reductase is involved in the oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine catalyzed by rat liver microsomes.[1]

References

  1. Formation of N-nitrosodiphenylamine from 1,1-diphenylhydrazine by rat liver microsomal preparations. Tatsumi, K., Kitamura, S., Sumida, M. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
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