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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins.

Mutations in the fushi tarazu (ftz) locus of Drosophila result in embryos with half the usual number of body segments. The sequences of the wild-type gene, a temperature-sensitive allele and a dominant mutant allele are presented. A portion of the conserved protein domain present in ftz and several homoeotic genes resembles the DNA-binding region of prokaryotic DNA-binding proteins, and is also similar to products of the yeast mating-type locus.[1]

References

  1. Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins. Laughon, A., Scott, M.P. Nature (1984) [Pubmed]
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