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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

UM- SCP-1, a new human cell line derived from a prostatic squamous cell carcinoma.

A permanent cell line (UM- SCP-1) has been established from a primary squamous cell carcinoma of the prostate. UM- SCP-1 has been passaged 40 times and has been in culture for 22 months. The doubling time of this aneuploid cell line is approximately 36 hr. In nude mice, UM- SCP-1 produces rapidly growing tumors with distinct histological features of squamous cell carcinoma. UM- SCP-1 cells express pemphigus and pemphigoid antigens and bind antibodies to beta 2 microglobulin and HLA-A,B,C common antigen. Cells of this line are unreactive with anti-A and anti-B blood group typing sera, autologous serum, and monoclonal anti-HLA-DR antibodies.[1]

References

  1. UM-SCP-1, a new human cell line derived from a prostatic squamous cell carcinoma. Grossman, H.B., Wedemeyer, G., Ren, L., Carey, T.E. Cancer Res. (1984) [Pubmed]
 
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