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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Endothelial cell origin of thorium oxide-induced angiosarcoma of liver.

A 72-year-old woman was found at autopsy to have hepatic angiosarcoma approximately 30 years after systemic thorium oxide (Thorotrast) injection. Intracytoplasmic localization of factor VIII-related antigen was demonstrated by an immunoperoxidase method, confirming the endothelial cell origin of the tumor.[1]

References

  1. Endothelial cell origin of thorium oxide-induced angiosarcoma of liver. Manning, J.T., Ordonez, N.G., Barton, J.H. Arch. Pathol. Lab. Med. (1983) [Pubmed]
 
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