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Purification and functional characterization of mutant LamB proteins.

The phage lambda receptor, or LamB, proteins have been purified from several missense lamB mutants, and the properties of the channel produced by these proteins were investigated in a reconstituted liposome system. In at least one mutant, a significant reduction in the sugar selectivity of the channel was observed, and another mutant protein interacted poorly with the maltose-binding protein immobilized on Sepharose beads.[1]


  1. Purification and functional characterization of mutant LamB proteins. Luckey, M., Nikaido, H. Ann. Microbiol. (Paris) (1982) [Pubmed]
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