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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei.

We have isolated cDNA and genomic clones containing alpha- and beta-tubulin genes from Trypanosoma brucei. Each clone has been mapped, and the identity of the tubulin genes has been established by cross-hybridization with cloned chicken tubulin genes and by hybridization-selection and translation of trypanosome tubulin mRNA. In contrast with the dispersed organization of tubulin genes in other organisms, trypanosome alpha- and beta-tubulin genes are physically linked and clustered in tandem repeats of approximately 13-17 copies per haploid genome of alternating alpha- and beta-tubulin sequences.[1]

References

  1. Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei. Thomashow, L.S., Milhausen, M., Rutter, W.J., Agabian, N. Cell (1983) [Pubmed]
 
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