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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The effect of naftidrofuryl (Praxilene) on intermittent claudication.

In a randomized double-blind controlled trial the effect of naftidrofuryl (Praxilene) 200 mg t.d.s., taken for 6 months, was compared with placebo in intermittent claudication. Whilst there was a significant subjective improvement regardless of age or treatment, patients over 60 on naftidrofuryl experienced a more rapid symptomatic relief than other patients. At six months this age group showed a significant improvement over the placebo group. There was no significnat objective evidence of improvement.[1]


  1. The effect of naftidrofuryl (Praxilene) on intermittent claudication. Waters, K.J., Craxford, A.D., Chamberlain, J. The British journal of surgery. (1980) [Pubmed]
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