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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Azidopolynucleotides as photoaffinity reagents.

Polynucleotides containing adenosine and 8-azidoadenosine or inosine and 8-azidoinosine residues have been prepared from mixtures of nucleoside diphosphates using polynucleotide phosphorylase from Escherichia coli. These copolymers can form complexes with polyuridylic or polycytidylic acids respectively. Single stranded poly(adenylic, 8-azidoadenylic acid) [poly(A,z8A)] has been used as a photoaffinity reagent to explore the subunit topography of RNA polymerase from E. coli.[1]

References

  1. Azidopolynucleotides as photoaffinity reagents. Cartwright, I.L., Hutchinson, D.W. Nucleic Acids Res. (1980) [Pubmed]
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