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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Ca2+- and calmodulin-dependent protein phosphorylation in rat lacrimal gland.

Ca2+, in homogenized lacrimal glands, enhanced phosphorylation of several peptides. Phosphorylation of two of these peptides was further stimulated by addition of the Ca2+-binding protein calmodulin and decreased by trifluoperazine, an inhibitor of Ca2+--calmodulin-dependent activity. Thus, Ca2+--calmodulin-dependent protein kinases and their substrates are present in lacrimal gland and could have an important role in lacrimal-gland function.[1]


  1. Ca2+- and calmodulin-dependent protein phosphorylation in rat lacrimal gland. Dartt, D.A., Guerina, V.J., Donowitz, M., Taylor, L., Sharp, G.W. Biochem. J. (1982) [Pubmed]
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