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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine.

Of 18 mentally retarded institutionalized subjects who had received long-term, high-dose treatment primarily with thioridazine or chlorpromazine, 2 developed definite corneal and lenticular opacities and 2 had equivocal ocular changes. In view of this finding, the authors suggest that alternative treatment, including different neuroleptics, be considered with mentally retarded institutionalized subjects; when that is not possible, subjects should be given periodic evaluation, including annual slit-lamp examination.[1]

References

  1. Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine. Gualtieri, C.T., Lefler, W.H., Guimond, M., Staye, J.I. The American journal of psychiatry. (1982) [Pubmed]
 
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