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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine.

Of 18 mentally retarded institutionalized subjects who had received long-term, high-dose treatment primarily with thioridazine or chlorpromazine, 2 developed definite corneal and lenticular opacities and 2 had equivocal ocular changes. In view of this finding, the authors suggest that alternative treatment, including different neuroleptics, be considered with mentally retarded institutionalized subjects; when that is not possible, subjects should be given periodic evaluation, including annual slit-lamp examination.[1]

References

  1. Corneal and lenticular opacities in mentally retarded young adults treated with thioridazine and chlorpromazine. Gualtieri, C.T., Lefler, W.H., Guimond, M., Staye, J.I. The American journal of psychiatry. (1982) [Pubmed]
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