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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Genetic polymorphism of coagulation factor XIIIB subunit in Japanese.

Genetic polymorphism of coagulation factor XIIIB subunit in Japanese has been described, using a thin-layer agarose gel isoelectric focusing followed by immunofixation. Phenotypes of factor XIIIB subunit were essentially classified into three common patterns A, B and AB. It is estimated that the phenotypes are determined by two codominant alleles. A new rare variant B' has been detected in Japanese. Gene frequencies calculated from 304 individuals showed FXIII-BA = 0.735, FXIII-BB = 0.252 and FXIII-BB' = 0.013, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.[1]

References

  1. Genetic polymorphism of coagulation factor XIIIB subunit in Japanese. Nakamura, S., Abe, K. Ann. Hum. Genet. (1982) [Pubmed]
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