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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Inhibition of rat adenocarcinoma metastases by "Staphylococcus aureus" protein A.

Fischer F 344/CRBL female rats were injected intravenously with 10(6) syngeneic 13,762 adenocarcinoma cells, and daily doses of either 10 micrograms, 100 micrograms or 1 mg Staphylococcus aureus protein A were administered intraperitoneally on days 1 through 11. The animals were sacrificed on day 12, their lungs infused with Bouin's solution, and lung metastases counted. A significant reduction in the number of visible metastatic nodules was observed in the animals given 100 micrograms and 1 mg of Staphylococcus aureus protein A daily.[1]

References

  1. Inhibition of rat adenocarcinoma metastases by "Staphylococcus aureus" protein A. Cowan, F.M., Klein, D.L., Armstrong, G.R., Ablashi, D.V., Pearson, J.W., Bensinger, W.I. Biomed. Pharmacother. (1982) [Pubmed]
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