Cryptococcal meningitis: treatment of three patients with miconazole.
Three patients with cryptococcal meningitis who were treated with miconazole are reported. All patients had previously received combination therapy with amphotericin B and flucytosine which was unsuccessful. All patients showed clinical improvement, and one obtained a mycological remission. Miconazole was well tolerated, and would appear to be a relatively non-toxic and effective drug in the treatment of cryptococcal meningitis which is refractory to conventional chemotherapy.[1]References
- Cryptococcal meningitis: treatment of three patients with miconazole. de Wytt, C.N. Med. J. Aust. (1981) [Pubmed]
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