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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis.

Free (approximately 1600 daltons) somatostatin-like immunoreactivity was identified in arterial plasma of dogs that had received a test meal. Neutralization of circulating somatostatin while the dogs were consuming a fatty meal increased the plasma concentrations of triglycerides, gastrin, pancreatic polypeptide, and insulin after the meal. It is concluded that, in the dog, somatostatin is a true hormone that regulates the movement of nutrients from the gut to the internal environment.[1]


  1. Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis. Schusdziarra, V., Zyznar, E., Rouiller, D., Boden, G., Brown, J.C., Arimura, A., Unger, R.H. Science (1980) [Pubmed]
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