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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Evidence for a vesicular transport mechanism in hepatocytes for biliary secretion of immunoglobulin A.

Quantitative electron microscopic autoradiography and diaminobenzidine cytochemistry provide evidence for an uptake and vesicular transport mechanism for iodine-125-labeled immunoglobulin A from plasma to bile by hepatocytes in vivo. The data confirm the existence of a hepatobiliary pathway for secretion of immunoglobulin A into the intestine and are consistent with a vesicular transport mechanism for biliary proteins within liver parenchymal cells.[1]

References

  1. Evidence for a vesicular transport mechanism in hepatocytes for biliary secretion of immunoglobulin A. Renston, R.H., Jones, A.L., Christiansen, W.D., Hradek, G.T., Underdown, B.J. Science (1980) [Pubmed]
 
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