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Kanoh, T. et al.

Suppression of in vivo tumor-induced angiogenesis by the protein-bound polysaccharide PSK.

The anti-angiogenic effects of an antitumor protein-bound polysaccharide, PSK, obtained from cultured mycelia of Coriolus versicolor in basidiomycetes were examined by the mouse dorsal air sac assay. PSK suppressed the mouse hepatoma MH134-induced angiogenesis when assessed by morphological and biochemical examinations. This finding suggested that the anti-metastatic effect of PSK is attributed to the suppression of tumor-induced angiogenesis.[1]

References

Suppression of in vivo tumor-induced angiogenesis by the protein-bound polysaccharide PSK. Kanoh, T., Matsunaga, K., Saito, K., Fujii, T. In Vivo (1994) [Pubmed]

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