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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A general method for selecting strains of Escherichia coli having altered spontaneous or induced mutabilities.

A simple method is described for selecting mutant strains of E. coli differing from their parent in the ability to spontaneously mutate via any mechanism. The method detects hypo- and hyper-mutators. It relies on the detection as papillae on thy colonies of second mutations either at the dra or drm locus.[1]

References

  1. A general method for selecting strains of Escherichia coli having altered spontaneous or induced mutabilities. Grigg, G.W. Mutat. Res. (1993) [Pubmed]
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