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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line.

A human T lymphoid cell line, PEER, dies by apoptosis in the presence of PMA and calcium ionophore. A new gene, TINUR, was cloned from apoptotic PEER cells. The expression of the TINUR gene is induced within 1 h after the cross-linking of the T cell Ag receptor complex. TINUR belongs to the NGFI-B/nur77 family of the steroid receptor superfamily and is an orphan receptor. TINUR binds to the same DNA sequence as NGFI-B/nur77. We also propose that the NGFI-B/nur77 family can be classified into two subtypes.[1]

References

  1. cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line. Okabe, T., Takayanagi, R., Imasaki, K., Haji, M., Nawata, H., Watanabe, T. J. Immunol. (1995) [Pubmed]
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