The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Behavior genetic analyses of drug withdrawal.

Many studies with rodent models have illustrated the role of genetic factors in determining the severity of ethanol withdrawal. In studies using inbred mouse strains and mice selectively bred for drug sensitivity, a consistent finding has been that genotypes susceptible to alcohol withdrawal are also susceptible to withdrawal from other drugs with CNS depressant effects. A new method for rough genetic mapping of genes associated with withdrawal, quantitative trait loci (QTL) gene mapping, has recently been employed in the BXD RI recombinant inbred mouse series. Several QTLs are associated with alcohol withdrawal: One such QTL on Chromosome 1 is described. An area of Chromosome 2 contains a QTL marker for a gene affecting withdrawal from acute and chronic ethanol, nitrous oxide, and high-pressure neurological syndrome Type I clonic convulsions.[1]


  1. Behavior genetic analyses of drug withdrawal. Crabbe, J.C., Belknap, J.K. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. (1993) [Pubmed]
WikiGenes - Universities