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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Cloning and expression of protein tyrosine phosphatase-like protein derived from a rat pheochromocytoma cell line.

A novel protein [designated protein tyrosine phosphatase-like protein (PTPLP)] which is distantly related to receptor-type protein tyrosine phosphatases (PTPases) was cloned from a rat pheochromocytoma cell line. The PTPLP was detected exclusively in the brain. Overexpression of the PTPLP decreased the basal PTPase activity of COS-7 cells for Raytide. These results suggest that PTPLP may function as a negative regulator of PTPases in neuronal tissues.[1]

References

  1. Cloning and expression of protein tyrosine phosphatase-like protein derived from a rat pheochromocytoma cell line. Kambayashi, Y., Takahashi, K., Bardhan, S., Inagami, T. Biochem. J. (1995) [Pubmed]
 
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