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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pharmacokinetics and pharmacodynamics of tizanidine.

The relationship among tizanidine dose, plasma concentration, and antispastic action is linear in nature. Response to a given dose of this agent varies among patients, and determining the appropriate clinical dose requires individual titration.[1]

References

  1. Pharmacokinetics and pharmacodynamics of tizanidine. Roberts, R.C., Part, N.J., Pokorny, R., Muir, C., Leslie, G.C., Emre, M. Neurology (1994) [Pubmed]
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