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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology.

The Rpt-1 gene product is an intranuclear protein expressed by CD4+ T-cells, which may regulate expression of the interleukin-2 receptor. Structural analysis of Rpt-1 reveals structural motifs that are shared by a group of transcriptional regulatory proteins with oncogenic potential. We suggest that altered expression of Rpt-1 may be associated with HTLV-I-dependent T-cell leukemias.[1]

References

  1. Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology. Patarca, R., Fletcher, M.A., Cantor, H. AIDS Res. Hum. Retroviruses (1993) [Pubmed]
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