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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pharmacokinetic profile of brodimoprim: oral bioavailability and penetration into interstitial fluid.

The bioavailability of brodimoprim tablets given orally is 80-90%; their relative bioavailability compared to an aqueous solution is 100%. Penetration of brodimoprim to suction skin blisters is 73 +/- 8%. The elimination half-life is longer from blisters than from serum. The relative stability of extravascular concentrations suggests that, with adequate dose sizes, dosage may be once daily, and even only once every second day.[1]

References

  1. Pharmacokinetic profile of brodimoprim: oral bioavailability and penetration into interstitial fluid. Bergan, T. Journal of chemotherapy (Florence, Italy) (1993) [Pubmed]
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