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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Effect of thyrotropin on ornithine decarboxylase and of polyamines on RNA polymerase in the thyroid.

Two major forms of RNA polymerase were partially purified from calf thyroid nuclei. Type I showed greatest activity in 30 mM(NH4)2SO4, transcribed native DNA best and was resistant to the inhibitor alpha-amanitin. Type II showed greatest activity in 100 mM(NH4)2SO4, transcribed denatured DNA template best and was sensitive to low concentrations of alpha-amanitin...[1]

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