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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sumatriptan relieves and prevents peri-operative migraine attacks.

The novel use of sumatriptan as an adjunct to the management of general anaesthesia in patients with a history of migraine is described. In two unpremedicated patients awaiting day surgery an acute pre-operative attack of migraine was successfully terminated by the injection of sumatriptan, allowing surgery to proceed uneventfully under general anaesthesia without postoperative complications. Two other patients with a history of severe habitual vomiting after general anaesthesia, who also had a history of migraine, were each given a prophylactic injection of sumatriptan after induction of anaesthesia and for the first time emerged from general anaesthesia free of these distressing complications.[1]


  1. Sumatriptan relieves and prevents peri-operative migraine attacks. Hannington-Kiff, J.G. Anaesthesia. (1993) [Pubmed]
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