Disease relevance of Postoperative Complications

• In the high-risk stratified group as defined by admission nutritional assessment and calculated PNI (greater than or equal to 50%), adequate preoperative TPN reduced postoperative complications 2.5-fold (p < 0.01), postoperative major sepsis six-fold (p < 0.005) and mortality five-fold (p < 0.01) [1].
• OBJECTIVE: To assess the impact of liver hypertrophy of the future liver remnant volume (FLR) induced by preoperative portal vein embolization (PVE) on the immediate postoperative complications after a standardized major liver resection [2].
• Further adjustment was made for seven postoperative complications (low cardiac output, cardiac arrest, perioperative myocardial infarction, prolonged mechanical ventilation, reoperation for bleeding or repeat cardiopulmonary bypass, stroke or coma, and mediastinitis), that were independently associated with operative mortality [3].
• In contrast, in patients with chronic liver disease, the hypertrophy of the FLR induced by PVE decreased significantly the rate of postoperative complications [2].
• Pulmonary hypertension has been described as associated with an increased peri- and postoperative complication rate and mortality [4].

Psychiatry related information on Postoperative Complications

• In this study midazolam had more advantages to the patient than diazepam; quicker onset of sedation, less pain during injection, profound anterograde amnesia and fewer postoperative complications being the main features [5].

High impact information on Postoperative Complications

• Nonfatal postoperative complications occurred in eight amiodarone-treated patients (12 percent) and in six patients receiving placebo (10 percent, P=0.78) [6].
• Only exposure to propofol, a lipid-based anesthetic agent, was significantly associated with the postoperative complications at all seven hospitals [7].
• Non-SCD-related postoperative complications were higher in both SS and SC patients who received regional compared with those who received general anesthesia (P =.095) [8].
• IL-6 levels correlated negatively with numerous markers of hepatocellular injury and the number of postoperative complications [9].
• There was also a higher incidence of total postoperative complications in the C-HCC group (60% vs. 37%, P < .05); however, regarding each individual complication, the rate was similar between the two groups [10].

Chemical compound and disease context of Postoperative Complications

• Improvements have continued after 2 yr of treatment in 10 patients (1 patient had a transplantation after he relapsed on withdrawal of ursodiol therapy; another died of postoperative complications of colon resection for carcinoma) [11].
• CONCLUSIONS: Complex hepatic resection can be performed with low mortality, and serum bilirubin is the single most powerful predictor of postoperative complication [12].
• Postoperative complications were detected by ECGs, creatine kinase and creatine kinase MB levels, and daily chart review [13].
• The clinical effect of combined warfarin and antiplatelet therapy on the incidence of stroke and postoperative complications after mitral (plus aortic) valve replacement was studied and compared with that observed with warfarin therapy alone [14].
• However, if adequate drainage is not possible, oral treatment with lactulose may help reduce postoperative complications [15].

Biological context of Postoperative Complications

• CONCLUSIONS: Cardiac troponin-I serum levels after open heart surgery in children and infants 4 h after admission to the ICU allowed anticipation of the postoperative course and correlated with the incidence of significant postoperative complications [16].
• There were no statistically significant differences in postoperative bilirubin clearance, alanine aminotransferase, prothrombin time, and frequency of postoperative complications among the three groups [17].
• Optimization of surgical procedures or therapeutic intervention that minimize hemolysis (e.g., off-pump surgery) or the resultant oxidative stress (e.g., antioxidant treatment) should be considered as possible strategies to lower the rate of postoperative complications in pediatric CPB [18].
• Epikeratophakia tissue lenses for the correction of myopia were removed from two patients as a result of postoperative complications such as stromal folds, complaints of glare, and decreased visual acuity [19].
• We determined the incidence of (1) conversion of the immunosuppressive regimen from cyclosporine and azathioprine alone (group I) to cyclosporine, azathioprine, and prednisone (group II), (2) late acute graft rejection (defined as occurring at greater than 1 postoperative year), and (3) major postoperative complications related to corticosteroids [20].

Anatomical context of Postoperative Complications

• Patients without postoperative complications exhibited stable and low urinary/pancreatic juice neopterin levels [21].
• PURPOSE: To review the results of adjustable suture surgery in patients with strabismus secondary to thyroid ophthalmopathy to determine long-term outcome and to identify postoperative complications [22].
• Data collected included demographic data, cardiopulmonary risk factors, smoking status, history of previous or current abdominal wall hernia (incision, inguinal, umbilical, femoral), previous midline incision, suture type, and postoperative complications [23].
• However, the postoperative and decrement in percent CD4 lymphocyte proved to be the independent predictors of postoperative complications [24].
• OBJECTIVE: To examine the effect of hyaluronic acid, a high-molecular-weight glucosaminoglycan found in the extracellular matrix, on the formation of adhesions, a major source of postoperative complications [25].

Gene context of Postoperative Complications

• Only levels of TNF-alpha in the recipient before transplantation were found to be predictive of postoperative complications [26].
• Only two out of seven samples of patients with postoperative complications showed intraoperative pH-i levels lower than 7.32 and IL-8 levels higher than 60 pg/ml [27].
• The incidence of postoperative complications in the ICAM-1 positive staining group tended to be higher than that in the ICAM-1 negative group [28].
• The effectiveness of octapeptide somatostatin analogs in the management of chemotherapy- related and AIDS-related diarrhea and in reducing postoperative complications of pancreatic surgery have also been demonstrated [29].
• Perioperative IGF-1 levels were lower in patients with postoperative complications than in those without complications [30].

Analytical, diagnostic and therapeutic context of Postoperative Complications

• No differences were observed between control group and treatment groups (HEP, HEP/5-FU) for postoperative complications and number of hospitalisation days [31].
• PURPOSE: A heparin surface modified posterior chamber intraocular lens (IOL) was compared with a conventional polymethylmethacrylate (PMMA) IOL regarding postoperative complications caused by inflammation [32].
• Patients with inadvertent enterotomy had significantly more postoperative complications (P < 0.01) and urgent relaparotomies (P < 0.001), a higher rate of admission to the intensive care unit (P < 0.001) and parenteral nutrition usage (P < 0.001), and a longer postoperative hospital stay (P < 0.001) [33].
• AIM: To determine whether the use of azathioprine/6-mercaptopurine before colectomy is associated with an increased rate of postoperative complications [34].
• RESULTS: For all procedures, regardless of type of anticoagulation treatment, there was no difference in the incidence of postoperative complications, except for the increased incidence of return to surgery for graft thrombosis (P =.02), failing graft (P =.0004), and debridement (P =.01) in patients who received unfractionated heparin [35].

References