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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Glycosylated derivatives of benzophenone, benzhydrol, and benzhydril as potential venous antithrombotic agents.

A series of glycosylated derivatives of benzophenone, benzhydrol, and benzhydril has been synthesized and evaluated for potential activity as venous antithrombotic agents. Studies on structure-activity relationships revealed that compounds having an electron-withdrawing group in the benzhydril or benzhydrol moiety, and specifically those having the beta-D-xylopyranosyl structure in the sugar moiety, were good antithrombotic agents in a rat model of venous thrombosis.[1]

References

  1. Glycosylated derivatives of benzophenone, benzhydrol, and benzhydril as potential venous antithrombotic agents. Bellamy, F., Horton, D., Millet, J., Picart, F., Samreth, S., Chazan, J.B. J. Med. Chem. (1993) [Pubmed]
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