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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Prokaryotic members of a new family of putative helicases with similarity to transcription activator SNF2.

Cloning and sequence analysis of a new open reading frame from Bacillus cereus reveals the relationship to a recently identified family of putative eukaryotic transcription activators similar to the yeast SNF2 gene product. As a result of comparative analysis of sequence features conserved in all members of this family, a gene from a chilo iridescent virus, as well as a putative helicase from Escherichia coli (hepA), can also be grouped into this family. The unexpected presence of prokaryotic and viral sequences in the previously purely eukaryotic SNF2 family suggests a defined subgroup of DNA helicases present in all species, with specific function in transcription activation.[1]

References

  1. Prokaryotic members of a new family of putative helicases with similarity to transcription activator SNF2. Kolstø, A.B., Bork, P., Kvaløy, K., Lindback, T., Grønstadt, A., Kristensen, T., Sander, C. J. Mol. Biol. (1993) [Pubmed]
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