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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The multifunctional Ca2+/calmodulin-dependent protein kinases.

Ca2+ mediates the effect of many hormones, neurotransmitters and growth factors on contractility and motility, carbohydrate metabolism, cell cycle, gene expression and neuronal plasticity. Multifunctional Ca2+/calmodulin-dependent (CaM) kinase, CaM kinase Ia, CaM kinase Ib and CaM kinase IV are four of the kinases that mediate Ca(2+)-signaling pathways. Recent studies have clarified our understanding of their structure, regulation and function.[1]


  1. The multifunctional Ca2+/calmodulin-dependent protein kinases. Schulman, H. Curr. Opin. Cell Biol. (1993) [Pubmed]
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