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Nucleotide sequence of the 2 matrix protein genes (M1 and M2) of hirame rhabdovirus (HRV), a fish rhabdovirus.

We have cloned and sequenced the M1 and M2 protein genes of hirame rhabdovirus (HRV). The M1 protein gene was 684 nucleotides long, encoding 227 amino acids. Sequence comparisons between the M1 protein genes of HRV and infectious hematopoietic necrosis virus (IHNV) or viral hemorrhagic septicemia virus (VHSV) revealed similarities of 65.1 and 40.8% at the nucleotide level and 81.1 and 44.8% at the amino acid level. The M2 protein gene was 582 nucleotides long, encoding 193 amino acids. Sequence comparisons between the M2 protein genes of HRV and those of IHNV and VHSV revealed similarities of 71.3 and 45.4% at the nucleotide level and 86.0 and 57.0% at the amino acid level, respectively.[1]

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