Disease relevance of Hemorrhagic Septicemia, Viral

• Conformation- and fusion-defective mutations in the hypothetical phospholipid-binding and fusion peptides of viral hemorrhagic septicemia salmonid rhabdovirus protein G [1].
• The mRNA transcribed from the N gene of viral haemorrhagic septicaemia virus (VHSV) of salmonids has been cloned in Escherichia coli and expressed [2].
• Sequence comparisons between the M1 protein genes of HRV and infectious hematopoietic necrosis virus (IHNV) or viral hemorrhagic septicemia virus (VHSV) revealed similarities of 65.1 and 40.8% at the nucleotide level and 81.1 and 44.8% at the amino acid level [3].
• Japanese flounder, Paralichthys olivaceus juveniles were vaccinated against viral hemorrhagic septicemia (VHS) by intramuscular injection of 10 microg of a plasmid DNA vector which encodes the viral hemorrhagic septicemia virus (VHSV) glycoprotein (G) gene under the control of the cytomegalovirus promoter [4].

High impact information on Hemorrhagic Septicemia, Viral

• Characterization of intramolecular disulfide bonds and secondary modifications of the glycoprotein from viral hemorrhagic septicemia virus, a fish rhabdovirus [5].
• An RNA-binding domain in the viral haemorrhagic septicaemia virus nucleoprotein [6].
• Identification of the non-virion (NV) protein of fish rhabdoviruses viral haemorrhagic septicaemia virus and infectious haematopoietic necrosis virus [7].
• Four monoclonal antibodies directed against the viral nucleocapsid were produced; they all recognized the four viral hemorrhagic septicemia virus (VHSV) serotypes [8].
• Nucleocapsid gene sequence of a North American isolate of viral haemorrhagic septicaemia virus, a fish rhabdovirus [9].

Chemical compound and disease context of Hemorrhagic Septicemia, Viral

• The susceptibility of Atlantic halibut, Hippoglossus hippoglossus (L.), to viral haemorrhagic septicaemia virus (VHSV) was tested [10].
• PHL are susceptible to infection by the North American strain of viral hemorrhagic septicemia (VHS) virus, and are sensitive to the cytotoxic effects of naphthalene, a common environmental contaminant [11].
• A commercial plant extract derived from olive tree leaf (Olea europaea) (LExt) and its major compound, oleuropein (Ole), inhibited the in vitro infectivity of the viral haemorrhagic septicaemia virus (VHSV), a salmonid rhabdovirus [12].
• By using labeled and hydrated phosphatidylserine (PS), PS-binding to solid-phase 15-mer peptides (pepscan) could map putative phospholipid-binding regions of the glycoprotein G of viral haemorrhagic septicaemia virus (VHSV), a salmonid rhabdovirus [13].
• In addition, the Diseases of Fish (Control) Regulations have since been passed so that new European Union rules for the control of infectious salmon anaemia, viral haemorrhagic septicaemia and infectious haematopoietic necrosis may be enforced nationally [14].

Biological context of Hemorrhagic Septicemia, Viral

• A ribonuclease (RNase) protection assay (RPA) has been used to detect nucleotide sequence variation within the nucleoprotein gene of 39 viral haemorrhagic septicaemia virus (VHSV) isolates of European marine origin [15].
• The glycoprotein of viral hemorrhagic septicemia virus (VHSV): antigenicity and role in virulence [16].

Gene context of Hemorrhagic Septicemia, Viral

• Cloning and sequencing the messenger RNA of the N gene of viral haemorrhagic septicaemia virus [2].
• A viral hemorrhagic septicemia virus (VHSV), recombinant glycoprotein vaccine (VHSVg) and a DNA vaccine (pCMV-VHSg) were injected in Japanese flounder (Paralichthys olivaceus) [17].
• Protein G expression and cell-to-cell fusion of cells transfected with the G gene of viral haemorrhagic septicaemia virus (VHSV) has been characterised [18].
• Molecular cloning of the mRNA coding for the G protein of the viral haemorrhagic septicaemia (VHS) of salmonids [19].
• An immunoblot assay was used to identify the viruses of infectious pancreatic necrosis, infectious hematopoietic necrosis, and viral hemorrhagic septicemia [20].

Analytical, diagnostic and therapeutic context of Hemorrhagic Septicemia, Viral

• An antigen capture enzyme-linked immunosorbent assay (ELISA) based on the detection of the viral nucleocapsid (anti-N system) was developed for the diagnosis of viral hemorrhagic septicemia [8].
• Two monoclonal antibodies (MAbs), 1H10 and 1F10, have been selected against the denatured glycoprotein of the viral haemorrhagic septicaemia virus (VHSV) of salmonids by immunoblotting [21].
• Purification of the glycoprotein G from viral haemorrhagic septicaemia virus, a fish rhabdovirus, by lectin affinity chromatography [22].

References