The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Characterization of the fluorescence emission properties of 7-azatryptophan in reverse micellar environments.

The amino acid analogue 7-azatryptophan has attracted significant recent attention as a novel optical probe for protein structure, function and dynamics. We report here, for the first time, its fluorescence emission behavior in a membrane mimetic model system, namely reverse micelles of aerosol-OT in n-heptane, containing varying amounts of added H2O or D2O. Upon increase in the water/surfactant molar ratio from 0.5 to 50 the emission maximum undergoes a pronounced red shift (by 20 nm), which is accompanied by dramatic quenching of the fluorescence emission and sharp decrease in its average lifetime. These data are used to infer the microenvironments of the fluorophore in the reverse micelles. Furthermore, the highly sensitive dependence of the fluorescence emission parameters of 7-azatryptophan on the water content of the reverse micelles highlights its suitability as a probe for water restricted environments, with possible applications to interfacial regions of biomembranes.[1]

References

 
WikiGenes - Universities