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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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(2-Ethoxyethoxy)acetic acid: an unusual compound found in the gas chromatographic analysis of urinary organic acids.

An unknown acidic compound was detected in a number of urine samples from patients with a suspected metabolic disorder and some patients treated with chemotherapy. The structure of this compound has been characterized as (2-ethoxyethoxy)acetic acid, using a gas chromatography/ mass spectrometry/computer system. The authentic compound was synthesized and compared with the unknown. Urinary (2-ethoxyethoxy)acetic acid is assumed to be formed endogenously from an exogenous precursor, probably 2-(2-ethoxyethoxy)ethanol.[1]

References

  1. (2-Ethoxyethoxy)acetic acid: an unusual compound found in the gas chromatographic analysis of urinary organic acids. Kamerling, J.P., Duran, M., Bruinvis, L., Ketting, D., Wadman, S.K., de Groot, C.J., Hommes, F.A. Clin. Chim. Acta (1977) [Pubmed]
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