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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Increase of cytochrome b mRNA by bis(2-hydroxyethyl) trisulfide in J774A.1 cells.

The effect of a cytotoxic substance (bis(2-hydroxyethyl) trisulfide; BS-1), isolated from Bacillus stearothermophilus UK563, on messenger ribonucleic acid (mRNA) level in mouse macrophage-like J774A.1 cells was investigated by the method of differential display. The treatment of J774A.1 cells with BS-1 led us to detect the inducible gene. The sequence analysis revealed that the gene was identical to mouse mitochondrial cytochrome b. In fact, Northern blot analysis showed that cytochrome b mRNA in J774A.1 cells was increased by BS-1.[1]

References

  1. Increase of cytochrome b mRNA by bis(2-hydroxyethyl) trisulfide in J774A.1 cells. Kohama, Y., Iida, K., Itoh, S., Tsujikawa, K., Mimura, T. Biol. Pharm. Bull. (1996) [Pubmed]
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