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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Synovial chondromatosis of the metacarpophalangeal joint: case report and review of the literature.

Intra-articular synovial chondromatosis in the hand is rare but should be considered in the differential diagnosis of a swollen, stiff or painful joint. Other possible diagnoses include osteoarthritis, rheumatoid arthritis, gout, trauma and chronic infection, and unless enchondral ossification of loose bodies is seen the diagnosis of synovial chondromatosis may not be made preoperatively. A 69-year-old man with synovial chondromatosis of the metacarpophalangeal joint is reported. The joint was swollen and tender. He had not sustained trauma and there was no evidence of arthritis, involvement of other joints or infection. Complete synovectomy with removal of all loose bodies was successful and his symptoms resolved. Intra-articular synovial chondromatosis is a benign condition, but spontaneous resolution is the exception and surgical synovectomy remains the most effective treatment.[1]


  1. Synovial chondromatosis of the metacarpophalangeal joint: case report and review of the literature. Reed, S.C., Wright, C.S. Canadian journal of surgery. Journal canadien de chirurgie. (1996) [Pubmed]
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