Apolipoprotein E in neurology.
Apolipoprotein E became relevant for neurologists in 1993 when the association of the apolipoprotein E-epsilon 4 allele with familial and sporadic late-onset Alzheimer disease was reported. Since that time, more than 100 confirmations and many research papers have appeared. A large neurobiological literature concerning the role of apolipoprotein E in the metabolism of the central nervous system is developing.[1]References
- Apolipoprotein E in neurology. Roses, A.D. Curr. Opin. Neurol. (1996) [Pubmed]
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