The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound

Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

[search][options]

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chen, Y. et al.

Tonkinelin: a novel annonaceous acetogenin from Uvaria tonkinensis.

Further studies on the root bark of Uvaria tonkinensis Finet et Gagnep. (Annonacease) led to the isolation of a new Annonaceous acetogenin, tonkinelin (1). The structure of 1 was elucidated on the basis of spectral data and chemical evidence. This compound represents an unusual type of C37 Annonaceous acetogenin, having neither tetrahydrofuran (THF) nor epoxide rings and possessing only a vicinal diol in the hydrocarbon chain. Preliminary pharmacological tests showed that tonkinelin (1) inhibits human leukemia (HL-60) and human colon adenocarcinoma (HCT-8) cell lines in vitro.[1]

References

Tonkinelin: a novel annonaceous acetogenin from Uvaria tonkinensis. Chen, Y., Yu, D.Q. Planta Med. (1996) [Pubmed]

Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg