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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Limb-girdle muscular dystrophy 2C: clinical aspects.

The LGMD2C linked to chromosome 13q and related to a 35 KDa dystrophin-associated glycoprotein deficiency, is very similar to Duchenne muscular dystrophy with an autosomal recessive inheritance. It is characterized by a variability of the age of onset, the severity of the evolution and the severity of myopathic changes at the muscle biopsy. This variability was also present in the expression of the alpha-sarcoglycan between the same sibships and between different families.[1]


  1. Limb-girdle muscular dystrophy 2C: clinical aspects. Ben Hamida, M., Ben Hamida, C., Zouari, M., Belal, S., Hentati, F. Neuromuscul. Disord. (1996) [Pubmed]
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