The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Cell-specific heat-shock induction of Hsp23 in the eye of Drosophila melanogaster.

The expression of two small heat shock proteins (sHsp), Hsp23 and Hsp27, was examined by immunological approaches in the eye of Drosophila melanogaster. Neither Hsp23 nor Hsp27 is detectable in unstressed (23 degrees C) eyes but both proteins are induced by heat shock (35 degrees C). In response to heat stress, Hsp27 is expressed in all cells of the ommatidium including the cone, pigment and photoreceptor cells. However, the heat-induced expression of Hsp23 is restricted to a single cell type of the ommatidium, the cone cells, suggesting that Hsp23 is regulated by specific mechanisms acting to inhibit the expression of this polypeptide in some ommatidial cells. The cell-specific induction of Hsp23 under stress conditions does not seem to be regulated by the Drosophila melanogaster heat shock transcriptional factor (DmHSF). In both unstressed and stressed conditions, DmHSF is detected in all the different types of ommatidial cells where it is found associated with the nucleus. These observations suggest that factors, other than the heat shock transcriptional factor, are involved in regulating the expression of the hsp23 gene under stress conditions.[1]

References

  1. Cell-specific heat-shock induction of Hsp23 in the eye of Drosophila melanogaster. Marin, R., Demers, M., Tanguay, R.M. Cell Stress Chaperones (1996) [Pubmed]
 
WikiGenes - Universities