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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Photoreceptors

 
 
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Disease relevance of Photoreceptors

 

Psychiatry related information on Photoreceptors

 

High impact information on Photoreceptors

 

Chemical compound and disease context of Photoreceptors

  • Taken together, these results indicate that the photoreceptor and ganglion cells are distinguished by a rapid synthesis of choline-containing phospholipids, while acetylcholine synthesis is restricted to a few cells at both margins of the inner plexiform layer [15].
  • Phytobilins (light harvesting and photoreceptor pigments in higher plants, algae, and cyanobacteria) are synthesized from biliverdin IXalpha (BV) by ferredoxin-dependent bilin reductases (FDBRs) [16].
  • Together with earlier observations that the COOH-terminal domains of the plant phytochromes also have sequence similarity to the histidine kinases, these data suggest that the cyanobacteria utilize photoregulated histidine kinases as a sensory system and that the plant phytochromes may be evolutionary descendants of these photoreceptors [17].
  • Purification and characterization of three members of the photolyase/cryptochrome family glue-light photoreceptors from Vibrio cholerae [18].
  • Onset and severity of uveitogenic peptide (1-20) of interphotoreceptor retinoid-binding protein-induced experimental autoimmune uveoretinitis is accelerated in CD200(-/-) mice and although tissue destruction appears no greater than seen in CD200(+/+) mice, there is continued increased ganglion and photoreceptor cell apoptosis [19].
 

Biological context of Photoreceptors

 

Anatomical context of Photoreceptors

 

Associations of Photoreceptors with chemical compounds

 

Gene context of Photoreceptors

  • Severe norpA mutations in Drosophila eliminate the photoreceptor potential and render the fly completely blind [33].
  • The Egfr triggers cell recruitment in the eye, and sprouty- eyes have excess photoreceptors, cone cells, and pigment cells [34].
  • The photoreceptors in the Nrl-/- retina have cone-like nuclear morphology and short, sparse outer segments with abnormal disks [35].
  • A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy [36].
  • A developmental analysis of argos mutant eyes indicates that the mystery cells, which are usually nonneuronal, are transformed into extra photoreceptors, and that supernumerary cone cells and pigment cells are also recruited [37].
 

Analytical, diagnostic and therapeutic context of Photoreceptors

References

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