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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Biochemical studies on peptide alkaloids: induction of ion selective mitochondrial swelling.

The effect of frangulanine, a cyclopeptide alkaloid isolated from Hovenia dulcis Thunb., on mitochondrial swelling was studied. Frangulanine induced mitochondrial swelling in 0.15 M KCl solution at the concentration of 6.5 muM. The alkaloid showed ion selectivity on the induction of mitochondrial swelling. Upon addition of frangulanine, mitochondria underwent swelling in 0.15 M KCl or RbCl solution but in neither NaCl nor LiCl solution.[1]

References

  1. Biochemical studies on peptide alkaloids: induction of ion selective mitochondrial swelling. Kawai, K., Nozawa, Y., Ogihara, Y. Experientia (1977) [Pubmed]
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