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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

The trans-Golgi network: a late secretory sorting station.

Proteins synthesized on membrane-bound ribosomes are transported through the Golgi apparatus and, on reaching the trans-Golgi network, are sorted for delivery to various cellular destinations. Sorting involves the assembly of cytosol-oriented coat structures which preferentially package cargo into vesicular transport intermediates. Recent studies have shed new light on both the molecular machinery involved and the complexity of the sorting processes.[1]


  1. The trans-Golgi network: a late secretory sorting station. Traub, L.M., Kornfeld, S. Curr. Opin. Cell Biol. (1997) [Pubmed]
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