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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects.

We report the analysis of the distribution of the C677T mutation on the methylenetetrahydrofolate reductase (MTHFR) gene in prenatally diagnosed neural tube defects (NTD) cases and controls. In contrast to previous reports, we found the same distribution in fetuses with NTD and controls, which suggests that the MTHFR C677T mutation cannot be regarded as a genetic risk factor for NTD.[1]

References

  1. Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects. Mornet, E., Muller, F., Lenvoisé-Furet, A., Delezoide, A.L., Col, J.Y., Simon-Bouy, B., Serre, J.L. Hum. Genet. (1997) [Pubmed]
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